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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e65ed7819faeef8da675c8426ead9e393a39fa350e4f9e18ea8ea31ca619c08' 
  AND token = 'iSrbFCV1Tn5m7p4R6nWDGUdyp1dSC27n/JFwR8YfyPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}