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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2072a548372063277a6c2186664e4f31a23f25827fb505a209dd212081d4030' 
  AND token = 'FXWbNSiCG1Hi9H0r+uWxulYTTnt51o1aHHzA2fp8FxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}