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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4349ec72ce08535ca021a61e598d840a5a706a5121afdcd17a6f488a36832e61' 
  AND token = 'CBKd6ZvtobpAzrU5l/vegHQbIKGxJi2X/9L3EMAaoJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}