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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de269118ce030183d0a9742b5015c512f3a88903f0b446d0718e2714c8e3f44f' 
  AND token = 'lqv3YP1bHnYv3VT+kxtazhGBhumc0AgQ51FxSFbar8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}