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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a2c881c9bc5ea91262cc0c25aa1e6f918e0b4af8366a1432fedfa15645451b' 
  AND token = 'mCm9yN1pXRrCOwP4SRx8GtPfSGV3Hfzb3VKS5StcXDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}