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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221aa5f099a6e44c0da6809654bf354ec46b07d149fbd0c2eeead239d400fee5' 
  AND token = 'uRck7GH3XWmjzj19/Qq4IJEPsOfo8uBYXGb3Z8ET/G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}