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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78cc6dc4715f7f10dba44b5e1f3b5a422ea4db5a9a307f84bb34beddf42737c5' 
  AND token = '1PfJ3qI41B8k3noY9tA2EVnenJtFfSS3w489O2CeS0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}