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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c862bfe4f31cb04cea1dd8034045cc40012f19b2fee991fd97a3c8deb2f86b4' 
  AND token = 'ukXoHOqkuB38slJ/LNQjk/BUI6SElhAHkIPZ1RiS7AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}