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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af9111bcd1304cda7780e8d4ebf1f01836f20bf47b4e6bb87e979050ca299436' 
  AND token = 'FElaSucT6TkF9tDNYWWf/z3DYJNAE1jMatR3dg4rryE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}