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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd5c5027da2e7bb31803a56fbc63be566a9df7f2fbea7887d8916238889345f' 
  AND token = 'VBPf0RPgZXRklwMJETrNQicbA15nFYmVFKrmMuMMZ8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}