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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ecbbd6eb931de9578a0d9682fa214a22a606c66b530e56c75c65f5d0b3ecbcb' 
  AND token = 'kF/V9u0kT98p+uGkWW/8NKPzrxElDxs1GGrjgo8QzTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}