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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f17d54537bb00071b755333bdefba721eaa88a76ff431534a6778429c41133' 
  AND token = 'mcZ5nU97+e4/9f96lVbikbSWUeFxPhz76TWV28XPjZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}