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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be2c09416ca96583f85644b4dbd10f300b2701a82e60709f6498f04f5ef1160' 
  AND token = 'NdARn2bq+/0Ny2hGaVRD4AUNcXUVXYETPhfx51lo6zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}