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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c54d3e3577e26c6a5937e1a07d65121a915a904145674e8c2b37c0a0e615dc8' 
  AND token = 'TDWPWnauKyDk6QnYidngW9pdznBZG4dJpmcR35f8Aw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}