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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b65239a98508257031a1000b9bdfbf068b13c371f0c0013115b2da47cfca88' 
  AND token = 'fNot2h4gV/D5JrI4T8+FaDVTi41RLdVnjQEr1SgN51s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}