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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f078664856e20464d276db5805f9f13afa5387e697f2bd0477d1f9ca76eccf05' 
  AND token = '725Nl1n3dQsRHoEqrd+lMLqU+QRh0wzkph9kpmDsYUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}