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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f4f996845b7ce1aa847ea877d67567143bc8b25a8d1a2112b9d3585f246bed4' 
  AND token = 'jygr8UadDTrvk9ffPrDH7RLkDe4+hrheUdrR6B49IYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}