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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a889307051a6bd6140c5ed72cfd358838f8433bccf1bbb992ed1a3c42cb966' 
  AND token = 'B38k/+XALDb3IA/5+Cs2LDixy7g2gm0uuJGvU25OVIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}