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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2c5ac253b0385d5f08ac89ad10dc91c1743d6146154e3ebb46f8e62fbf5d22' 
  AND token = '1yNE7nIYDgNoSQ+yaapuau0cDF3dkvFOpQpVevW5pd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}