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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a483542e3d132cf81ebac7b605bdb09a3596fbf573359d67063308bba60159c' 
  AND token = 'JBALY2bomxZp64QIpoKfrb2LJ+PxFdMgORz3YHN2TwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}