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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c588b023d6a1388f6b4085655e705870dd690c80c9c7eb1676bba0e3588784' 
  AND token = 'CXtof5QmYHViqXvEfDuNqC1ockrxB1iKsjcfBA+0qds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}