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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c40d4b3f3195c8b940b9f5698ad6ee90ea4de78ee5ddeb5f5fdf2ec91ea405' 
  AND token = 'nGzqnDQIFlW+x6YzdXcK+dBCaMl7pqlBKXLyLmC1bhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}