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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1acf22a59808beb7797ef3cdbb140c8665c20e470a687ab5d59ef73b466e2f05' 
  AND token = 'HPC8qDoNu8t5+l8zyFDbklPvX5aUIHcdmU4Ln5MU1JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}