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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3fb19413d051bd711f239a4c6701f789654211dd207814290811e18f768f54' 
  AND token = 'kBIYAIwIrwW0fjgW9y2B86JV5Cv1hjYBBKBPNV/6p7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}