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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20aeb29ef1c8bbcbe79b1b19912d1c328eb4a674f465f085c22df3708d507b1e' 
  AND token = 'Mliayc3/rL4rWpJI2mK9vmqe+LQ1VRhr8m1hDCjz4m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}