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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b7b08e3b87803a73033cb1860d46ab7fb0382f1f0e2b4ace464a9969e74969e' 
  AND token = 'HO//AeWg6oBGtJ/FOcoC4Ptv79AtAlz/cBvGsflTwZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}