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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4506e576b002823e5e376b43e3ba9584b421fd8120a41dded24df750554ba309' 
  AND token = 'sDOVlONX87aq6x2Cx0/hlT/cYt9gV3N4g+L6/7+wY14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}