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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fc8104cff2c0d4d69417b7ba44d1cee1a63d28378051ba4134d4be0656b9c0' 
  AND token = 'FYpdPqtL5XJ9heQLsxtGYnqPEmQw41XQHOkUAAxN7Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}