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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15aeeb0999dfd0aa77e6eee2eb8b38c330e2119bb34a10d26d844c1df7fb7154' 
  AND token = 'VDr38A54D3NrPFzmUNldbDyQtAWoduYqwQFXzZszMa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}