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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4359380aa3472d8363b3f3142ec8f71ca564de765bb7fe161a5e6cf12a218b18' 
  AND token = '5+HnHgx4rnSWMyDxRZ2zixI2U3Mrr3KnQuuB/raYByY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}