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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5627ba9fb5fe517638f91bae5e358ef94711765218fa34c9296c37e35d618edd' 
  AND token = '0UL6N1gWzObu6gFN0pjOZXlgS1/XbXZQj+Q2AAX/yI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}