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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b48942fcbef694091e79bd16cb10cf3f9f329e7c254784faec2aa02febc79da' 
  AND token = '8CeKi1B8dZI+ANIWF8IaljSF09ONFFu5sN7n41q2msY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}