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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c7dd89251905e9c70a2b66d12c518d5d4dff79e49b87e2def89c586478b886' 
  AND token = 'YWHWi6EB2KY7fC5xDo6t4KnOKrAQu6gwiCjv1TvDu0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}