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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2817e06850decfc1a3ab6b615c15fd0e996df859a472012e762b315f792b7e2e' 
  AND token = 'aezmK9WZ/DIjWp3C6p4CvB8VYrw9nSNDVSWlRcVru54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}