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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '695f83e18d86c927be642fcd004e788f123a6beff665d8435d3cfa29bd034a33' 
  AND token = 'koPPtAMH80ol2U7yPaneeUCZdg1OOJpjLrn1lfpho5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}