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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f5628ab1cc2a61b49b2c16624c2a09d6c2351a8f73f293e84735d0f0dc8c96' 
  AND token = 'LunH+93TCcmrxutZiayB3XqWDS7qjdPC54Ag9ELBPzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}