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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fa21060ae8c377cba18e5feacd910fa0664c2973ae5f8ac867153354ea84458' 
  AND token = 'mxN5fmA+O0Xe9AFIP2CDAC1lKHQdCmiPLs+aBIZgFow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}