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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef7439b8269935be681087324e5ed014f0e013961cac68abac12339594952e2' 
  AND token = 'eB3MlXM9gCyvczIQpTx2SWn21wYdjX2HjPYuXuCl2LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}