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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a777cf6108a56b43eb644d1e8d023d60872f09428b4d8a073c0b29b7a85966d' 
  AND token = 'H4eHI0Z2z9EbL3JZ+WWebHrJ1a1GCSIiZY+lJ1i1i6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}