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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd16100bba45bb2204ca8193ed939bac33e95d07ac02b9196bbb71f6fb4256c' 
  AND token = 'RK+4XpbUQbvx4WXmP0uu+22cmB+iVJg7M9MShF8kfyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}