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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7fd25cf111c28d9fc0eac0b5168418650a11e33c72cf6af99e4373efb10082' 
  AND token = 'fNYFUxmxn/W+eH5edbPpx98kF77wkQWAyrjtgQa1GFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}