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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d7011e700e16dd2a559030c3b78e53bdada47b07b6e02c217e9caf9de2c765' 
  AND token = 'AonowsCmoGbJLHt8ho/mFAg4SbGQRuzWZuxtJ8N7OG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}