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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b59edcd065d1eb77d52ac5c1aa40c45c87f683e64264c9d4b95ee16fe65cfaa' 
  AND token = 'J8k4HS3U/uzkN2hhU+QV53CwICllptAqgk/PxD+MDu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}