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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2bf381a770986339cbda141c5407e0ec3a885b84597b1949edfa82a12b77d20' 
  AND token = 'ITySHHmjzngNn0WWZ+3vnLHTlu5lZ06k7irx82TlTro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}