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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75274359ff9a738e52833802a96beeb06e975c298050c1195b6d63b719105f95' 
  AND token = 'ANTu1O4baqu6r3OABAoKHkhO5L8gMHG5u1gm5v7IIU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}