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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3642a8cb0d569b5fe46810cf0273e71a62b022d825b8527a3be7c364170fe830' 
  AND token = 'bS6K2Mx6CeJAxrHYjTTPcboj/TTaK+H8kG/pRO+MbCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}