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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65212048e9492113da74dd4759c86994002e66225d7c4ea3d15763794d56dd57' 
  AND token = 'pf1yIEWTi2YJQvt9Fmga/f+vyiTrkbdqS6qiMyRqj34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}