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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80bd9f6d14fd0b6bd13bd9ca9722a7f6885afd4ab767a7002ea256dd0a89597' 
  AND token = 'k1FzRDr2Z2kNB4IetOVSG/RZ3VLLhJnBmnBRt2/10ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}