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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7929450b5f78faf6dadd47e862ba0fa1868e885a381db50f5195e71afc8a12' 
  AND token = 'wS7DMkO6SWbb1KwLCpnBSEA7WBHImMo7oTXUtvD+DtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}