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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acacf7a321c8ca6b651cc48d31cd777e6b9784f29fc03cd0490bc830f33761c5' 
  AND token = 'rIs62sRt1Yq/i30aLKNdRruMP0qW2LMLKQUaEwyh9v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}